generative-ai
Mentors and Regional Facilitators
| Name | Region | Skills | Interests |
|---|---|---|---|
| Aniruddha Maiti | ACCESS CSSN, Campus Champions | ||
| Devin Bayly | ACCESS CSSN, Campus Champions, CCMNet | ||
| Brandon Biggs | OnDemand | ||
| David Ryglicki | |||
| Fan Chen | ACCESS CSSN | ||
| Feseha Abebe-Akele | CCMNet | ||
| Mattie Niznik | Campus Champions |
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Upcoming Events & Trainings
| Title | Date |
|---|---|
| NAIRR Pilot Office Hours | 5/13/25 |
| NAIRR Pilot Office Hours | 5/27/25 |
| NAIRR Pilot Office Hours | 6/10/25 |
Topics from Ask.CI
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Knowledge Base Resources
| Title | Category | Tags | Skill Level |
|---|---|---|---|
| Intro to GenAI Chatbot | Learning | ai, generative-ai | Beginner |
| Leveraging AI in Generative Assets and Environments for Play: Insights from the English Department's Digital Media Lab | Slides | ai, llm, generative-ai, reinforcement-learning, supervised-learning, unsupervised-learning, deep-learning, machine-learning, neural-networks, big-data, image-processing | Beginner |
| Tutorial: Localized RAG Chatbot with ACCESS HPC | Tool | ai, llm, generative-ai, nlp, machine-learning, ACCESS, supplement, jetstream, cloud-open-source, natural-language-processing, bash, git, vm, community-outreach, research-facilitation, workforce-development, python, interactive-mode, easybuild, pip | Beginner, Intermediate |
Engagements
Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
- Summary and objectives of the proposed experiments:
- An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
- Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
- Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
- Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress
People with Expertise
Feseha Abebe-Akele
Elizabeth City State University
Programs
CCMNet
Roles
mentor, researcher/educator, research computing facilitator, CCMNet
Expertise
Expertise
Expertise
People with Interest
Interests
Kevin Brandt
South Dakota State University
Programs
Great Plains, CCMNet
Roles
regional facilitator, Affinity Group Leader, CCMNet
Interests
Kevin Brandt
South Dakota State University
Programs
Campus Champions, Great Plains, CCMNet
Roles
regional facilitator, representative, research computing facilitator, Affinity Group Leader, CCMNet PM, CCMNet
